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HOW LIFE WORKS

A USER’S GUIDE TO THE NEW BIOLOGY

A bold effort to create a new language that forces a “rethinking” of “thinking itself.”

Generating a new language for the book of life.

Life is not all about tidy genetic blueprints; it is influenced by "messy and capricious" elements so many levels that genes are “just ingredients for creating a palette of...possibilities,” writes Ball, a former longtime editor at Nature and author of many books about science and nature. He first examines old biological tenets gone wrong, such as the notion that one gene is equal to one protein, or that correcting single gene mutations can “cure” most diseases. Language, writes the author, is the only “human technology” that bears any resemblance to the “mechanism of life...undoubtedly because it is a kind of ‘organic technology’ as much a part of our biological nature as is our flesh and blood, our minds, our cultures." Like life, when “you reduce it to its component parts, you lose its meaning.” Later, the author continues, “meaning carries a lot of baggage in biology, and you’ll rarely see it used in an academic text on the topic. But it’s a crucial concept, because it conveys a large part of what distinguishes life from other states of matter.” Many DNA sequences linked to complex traits and diseases are outside the “coding” genome,” and genes that generate fins can be “readily redirected to make an arm…Rapid phenotypic change is possible precisely because so little is demanded of the genes themselves.” In showing that complex life is more “emergent” than “programmed,” Ball takes on many conventional notions about biology. “We are at the beginning of a profound rethinking of how life works,” he writes. Evolution has consistently invented new ways of creating living beings, and it will continue to do so. “The challenge,” writes the author, “is to find a good way of talking about these vital stratagems,” and his latest book offers plenty of food for thought for scientists in disciplines from medicine to engineering.

A bold effort to create a new language that forces a “rethinking” of “thinking itself.”

Pub Date: Nov. 6, 2023

ISBN: 9780226826684

Page Count: 520

Publisher: Univ. of Chicago

Review Posted Online: Aug. 24, 2023

Kirkus Reviews Issue: Sept. 15, 2023

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ELON MUSK

Alternately admiring and critical, unvarnished, and a closely detailed account of a troubled innovator.

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A warts-and-all portrait of the famed techno-entrepreneur—and the warts are nearly beyond counting.

To call Elon Musk (b. 1971) “mercurial” is to undervalue the term; to call him a genius is incorrect. Instead, Musk has a gift for leveraging the genius of others in order to make things work. When they don’t, writes eminent biographer Isaacson, it’s because the notoriously headstrong Musk is so sure of himself that he charges ahead against the advice of others: “He does not like to share power.” In this sharp-edged biography, the author likens Musk to an earlier biographical subject, Steve Jobs. Given Musk’s recent political turn, born of the me-first libertarianism of the very rich, however, Henry Ford also comes to mind. What emerges clearly is that Musk, who may or may not have Asperger’s syndrome (“Empathy did not come naturally”), has nurtured several obsessions for years, apart from a passion for the letter X as both a brand and personal name. He firmly believes that “all requirements should be treated as recommendations”; that it is his destiny to make humankind a multi-planetary civilization through innovations in space travel; that government is generally an impediment and that “the thought police are gaining power”; and that “a maniacal sense of urgency” should guide his businesses. That need for speed has led to undeniable successes in beating schedules and competitors, but it has also wrought disaster: One of the most telling anecdotes in the book concerns Musk’s “demon mode” order to relocate thousands of Twitter servers from Sacramento to Portland at breakneck speed, which trashed big parts of the system for months. To judge by Isaacson’s account, that may have been by design, for Musk’s idea of creative destruction seems to mean mostly chaos.

Alternately admiring and critical, unvarnished, and a closely detailed account of a troubled innovator.

Pub Date: Sept. 12, 2023

ISBN: 9781982181284

Page Count: 688

Publisher: Simon & Schuster

Review Posted Online: Sept. 12, 2023

Kirkus Reviews Issue: Oct. 15, 2023

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THE ELEPHANTS OF THULA THULA

A heartwarming and inspiring story for animal lovers.

The third volume in the Elephant Whisperer series.

In this follow-up to An Elephant in My Kitchen, Malby-Anthony continues her loving portrait of the Thula Thula wildlife reserve, which she co-founded in 1998 with her late husband, South African conservationist Lawrence Anthony, who published the first book in the series, The Elephant Whisperer, in 2009. Following his death in 2012, Malby-Anthony sought to honor his legacy by continuing his vision “to create a massive conservancy in Zululand, incorporating our land and other small farms and community land into one great big game park.” At the same time, the elephants gave her “a sense of purpose and direction.” In the Zulu language, thula means quiet, and though the author consistently seeks to provide that calm to her charges, peace and tranquility are not always easy to come by at Thula Thula. In this installment, Malby-Anthony discusses many of the challenges faced by her and her staff, particularly during the Covid-19 pandemic. These included an aggressive, 2-ton rhino named Thabo; the profound loss felt by all upon the death of their elephant matriarch, Frankie; difficulty obtaining permits and the related risk of having to relocate or cull some of their animals; the fear of looting and fire due to civil unrest in the region; and the ongoing and potentially deadly struggles with poachers. Throughout, the author also shares many warm, lighthearted moments, demonstrating the deep bond felt among the humans and animals at the reserve and the powerful effects of the kindness of strangers. “We are all working in unity for the greater good, for the betterment of Thula Thula and all our wildlife….We are humbled by the generosity and love, both from our guests and friends, and from strangers all around the world,” writes the author. “People’s open-hearted support kept us alive in the darkest times.”

A heartwarming and inspiring story for animal lovers.

Pub Date: April 25, 2023

ISBN: 9781250284259

Page Count: 320

Publisher: St. Martin's

Review Posted Online: Feb. 22, 2023

Kirkus Reviews Issue: March 15, 2023

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